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How to Cite This article

Wang Zhongyu, Zhang Sumei, and Bai Jiangyan (2025).  A case presentation of a patient diagnosed with acute cerebral infarction and myasthenia gravis. Journal of Multiscale Neuroscience, 4(1): 57-63.

DOI:   https://doi.org/10.56280/1681013056

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Authors Affiliation

  Wang Zhongyu 

  Chongqing Medical University, Chongqing 400016, China

  Zhang Sumei

  Department of Neurology, Taiyuan Central Hospital, Shanxi        Province, 030009, China

  Bai Jiangyan

  Department of Neurology, Taiyuan Central Hospital, Shanxi        Province, 030009, China

  Received     7  February 2025           

  Accepted    5  February 2025             

  Online published   15  March  2025

Comment for this article

​​​

                 A case presentation of a patient diagnosed with acute cerebral infarction
and myasthenia gravis

CLINICAL CASE REPORT

Publication:   Journal of Multiscale Neuroscience                DOI:   https://doi.org/10.56280/1681013056

 

Abstract

A 78-year-old male patient presented to Taiyuan Central Hospital with complaints of speech impairment, intermittent right eyelid drooping, and occasional diplopia. The patient, who had semantic dementia, exhibited progressively worsening symptoms. He had a medical history of coronary heart disease and hypertension. Physical examination revealed impaired short-term memory and arithmetic ability, ptosis of the right upper eyelid severe enough to cover the cornea, restricted outward movement of the left eye, and decreased bilateral knee and ankle reflexes. No other abnormalities were detected. Magnetic resonance imaging (MRI) showed cerebral infarction in the right temporal lobe. Based on these findings, differential diagnoses included myasthenia gravis and paraneoplastic neurological syndromes. Repetitive nerve stimulation and neostigmine tests supported the diagnosis of myasthenia gravis. Clinically, the coexistence of acute cerebral infarction and myasthenia gravis is rare. Due to the overlap of symptoms, the diagnosis requires a comprehensive evaluation of relevant symptoms and tests.

Keyword: Acute cerebral infarction, myasthenia gravis, coronary artery disease, hypertension, autoimmune neuromuscular disease

Conflict of Interest

The authors declare no conflict of interest

                
Copyright: © 2025 The Author(s). Published by Neural Press.

This is an open access article distributed under the terms and conditions of the CC BY 4.0 license.

Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, Neural Press™  or the editors, and the reviewers. Any product that may be evaluated in this article, or claim that made by its manufacturer, is not guaranteed or endorsed by the publisher.

References:

Gwathmey, K.G. & Burns, T.M. (2015) Myasthenia gravis. Seminars in Neurology 35, 327-39.

Sasi, S.  Mohamed, M.,   Chitrambika, P. &  Yassin, M. (2022)  Myasthenia gravis and myeloproliferative

neoplasms - Mere association or paraneoplastic neurologic syndrome: A mini-review. Acta Biomedica 92, e2021437.

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