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Online ISSN 2653-4983
JOURNAL of MULTISCALE NEUROSCIENCE
How to Cite This article
Wang Zhongyu, Zhang Sumei, and Bai Jiangyan (2025). A case presentation of a patient diagnosed with acute cerebral infarction and myasthenia gravis. Journal of Multiscale Neuroscience, 4(1): 57-63.
DOI: https://doi.org/10.56280/1681013056

Authors Affiliation
Wang Zhongyu
Chongqing Medical University, Chongqing 400016, China
Zhang Sumei
Department of Neurology, Taiyuan Central Hospital, Shanxi Province, 030009, China
Bai Jiangyan
Department of Neurology, Taiyuan Central Hospital, Shanxi Province, 030009, China
Received 7 February 2025
Accepted 5 February 2025
Online published 15 March 2025
A case presentation of a patient diagnosed with acute cerebral infarction
and myasthenia gravis
CLINICAL CASE REPORT
Publication: Journal of Multiscale Neuroscience DOI: https://doi.org/10.56280/1681013056
Abstract
A 78-year-old male patient presented to Taiyuan Central Hospital with complaints of speech impairment, intermittent right eyelid drooping, and occasional diplopia. The patient, who had semantic dementia, exhibited progressively worsening symptoms. He had a medical history of coronary heart disease and hypertension. Physical examination revealed impaired short-term memory and arithmetic ability, ptosis of the right upper eyelid severe enough to cover the cornea, restricted outward movement of the left eye, and decreased bilateral knee and ankle reflexes. No other abnormalities were detected. Magnetic resonance imaging (MRI) showed cerebral infarction in the right temporal lobe. Based on these findings, differential diagnoses included myasthenia gravis and paraneoplastic neurological syndromes. Repetitive nerve stimulation and neostigmine tests supported the diagnosis of myasthenia gravis. Clinically, the coexistence of acute cerebral infarction and myasthenia gravis is rare. Due to the overlap of symptoms, the diagnosis requires a comprehensive evaluation of relevant symptoms and tests.
Keyword: Acute cerebral infarction, myasthenia gravis, coronary artery disease, hypertension, autoimmune neuromuscular disease
Conflict of Interest
The authors declare no conflict of interest
Copyright: © 2025 The Author(s). Published by Neural Press.
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