JOURNAL of MULTISCALE NEUROSCIENCE

BRIEF REPORT

The concept of dynamic multiscaling has changed our approach to multi-neuronal cable theory. Previously, computational neuroscientists considered individual neurons as neural masses or compartmental models, but now a distributed representation of single neurons as ionic cable structures is most likely to lead to a greater understanding of how the distribution of ionic channels and synaptic input along the dendrites of a few neurons can offset the collective behavior of a large ensemble of neurons and, therefore, provide a measure of the dynamical brain. This change in perspective forms the basis of volume conductor-bidomain modeling, a new method that captures multiscalar electrophysiology.

​

Keywords:  Multiscalar electrophysiology; neuropil; volume conductor; bidomain model; Nernst-Planck equations; ionic diffusion; field potentials, ionic cable theory

​

Conflict of Interest

The author declares that he was an editorial board member of JMN, at the time of submission. This had no impact on the peer review process and the final decision.

​

This article belongs to the Special Issue                

Dynamic Multiscaling in Neuroscience

    Lead Editor:  Dr. Nicolangelo Iannella

         University of Oslo, Norway

​

Copyright: © 2024 The Author(s). Published by Neural Press.

This is an open access article distributed under the terms and conditions of the CC BY 4.0 license.

​

Desclaimer

All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors, and the reviewers. Any product that may be evaluated in this article, or claim that made by its manufacturer, is not guaranteed or endorsed by the publisher.